Name:
A Video Summary of the Evolution of the RebiSmart® Electromechanical Autoinjector to Improve Usability in Support of Adherence to Subcutaneous Interferon Beta-1a Therapy for People Living with Multiple Sclerosis
Description:
A Video Summary of the Evolution of the RebiSmart® Electromechanical Autoinjector to Improve Usability in Support of Adherence to Subcutaneous Interferon Beta-1a Therapy for People Living with Multiple Sclerosis
Thumbnail URL:
https://cadmoremediastorage.blob.core.windows.net/21a718fc-69e6-45b0-b327-864be928e150/videoscrubberimages/Scrubber_6.jpg
Duration:
T00H07M04S
Embed URL:
https://stream.cadmore.media/player/21a718fc-69e6-45b0-b327-864be928e150
Content URL:
https://cadmoreoriginalmedia.blob.core.windows.net/21a718fc-69e6-45b0-b327-864be928e150/VJBM-2023-0015 Final BRANDED.mp4?sv=2019-02-02&sr=c&sig=A%2BBEZyiN58%2F5grzwNKIkGddKWMIG6yqQCDnv9QQO65g%3D&st=2024-11-23T14%3A00%3A44Z&se=2024-11-23T16%3A05%3A44Z&sp=r
Upload Date:
2024-07-03T00:00:00.0000000
Transcript:
Language: EN.
Segment:1 Introduction.
DR DOMINIC JACK: [MUSIC PLAYING] So welcome, everybody. My name is Dominic Jack. I'm from Global Research and Development at Merck KGaA, Darmstadt, Germany. And on behalf of the authors, I would like to present the Evolution of the RebiSmart® Electromechanical Autoinjector to Improve Usability and Support of Adherence to Subcutaneous Interferon Beta-1a Therapy for People Living with Multiple Sclerosis.
Segment:2 Background.
DR DOMINIC JACK: Subcutaneous interferon Beta-1a or Rebif is a well-established and effective therapy for people living with multiple sclerosis, or MS for short. People living with MS who adhere to their treatment schedule and who persist with their prescribed treatment experience fewer relapses. The RebiSmart® Electromechanical Autoinjector was designed to be easy to use, and in turn, support people living with MS to adhere to their treatment. However, the design of the device needs to regularly evolve to meet the changing needs of people living with MS. The article discussed here reports on the next-generation device, RebiSmart® 3.0, and describes a series of studies that were undertaken to validate its safe use, and includes a survey of user needs.
Segment:3 Formative usability studies.
DR DOMINIC JACK: Participants in the final formative study were generally positive about the device. They appreciated the size, screen clarity, device safety, and notification sounds. Recommendations to improve the safety and future design of the device were incorporated, such as increasing the size of the pin digits and adding texture on the sides to help with grip for those with dexterity issues.
DR DOMINIC JACK: fed into the safety and future design of the device. The findings and recommendations were evaluated an updated prototype RebiSmart® device. In the final formative study, a further nine participants as well as determine recommendations for improvement. and potential use of difficulties, These studies were designed to identify this device's strengths including the RebiSmart® device. evaluating two electromechanical autoinjectors, were conducted with 46 participants initially A series of formative usability studies
Segment:4 Summative usability study.
DR DOMINIC JACK: The subjective assessment relied on participants' own opinions. Here, 43 out of 45 participants considered the product safe to use as is. Two participants suggested modifications to increase the clarity of the warning screens, and to include a wrist strap.
DR DOMINIC JACK: 45 participants evaluated the updated RebiSmart® 3.0 device. Critical tasks were defined as tasks which, if performed incorrectly or not performed at all, could or would cause serious harm to the patient or user. They were assessed through a sequence of simulated use scenarios and knowledge tasks with a particular focus on any safety concerns. The device had to be safe for the intended users in the intended use environments. All user errors, instances of moderator assistance, close calls, and difficulties during device operation were recorded.
DR DOMINIC JACK: For the use scenarios, most instance of user errors occurred with participants not inspecting the new cartridge correctly, not washing their hands, not disinfecting the injection site, and not disposing of the cartridge appropriately. The root causes of these use errors were due to participants' existing habits and perceptions, and the simulated environment of the test session. The outcome was to reinforce the training.
DR DOMINIC JACK: Moving on to the knowledge tasks. The first of which concerned the knowledge check and the participants' understanding of the instructions for use. As before, user errors occurred due to participants relying on their existing knowledge, habits, and prior understanding. But these errors reduced noticeably after reading the instructions for use. As a result of this first knowledge task, the on-screen text reminders and training notes were updated to prompt users to read the instructions for users.
DR DOMINIC JACK: The second knowledge task was a paper-based screen reading comprehension test to simulate understanding on-screen instructions. Most user errors occurred with participants not stating the correct procedure due to the instructions being unclear. As a result, the on-screen text was updated to help users follow the on-screen instructions. In the following summative usability study,
Segment:5 User needs survey.
DR DOMINIC JACK: New users, those that were RebiSmart®-naive, rate the new device, and experienced users, those who had used a previous design of the RebiSmart® compared the new device with the current RebiSmart® device. RebiSmart®-naive participants rated the new device an average of 4.3 out of 5. RebiSmart®-experienced participants also gave a similar average score of 4.4 out of 5, rating the new device 4.6 out of 5 for being easy to use compared with their current RebiSmart® device.
DR DOMINIC JACK: with answers scored on a 5-point scale. Overall, the participants had a very positive perception of the ease of changing injection settings, customizability, and were comfortable taking the device out in public. The participants then responded to a series of feedback statements scored on a 5-point scale. For example, participants rated the device 4.7 out of 5 in terms of being as easy to use as a smartphone, with over 75% of participants awarding it the highest rating. statements to assess the device's usability and design Participants responded to a series of questions and feedback acceptance of user needs. was set up to evaluate the customer or market safe and effective, a user needs survey In addition to validating that the device was
Segment:6 Conclusions.
DR DOMINIC JACK: The formative studies identified some improvements for the device. The safe use of RebiSmart® 3.0 was confirmed through the evaluation of a series of use scenarios and knowledge tasks in the summative study. Participants showed a high level of satisfaction with the device's usability and design, independently from previous use of RebiSmart® as shown in the user needs survey. These outcomes have demonstrated the successful evolution of the next-generation device, RebiSmart® 3.0.
Segment:7 Closing.
DR DOMINIC JACK: [MUSIC PLAYING]
