Name: Autoimmune disease research solutions
Uploaded: 2025-06-17T00:00:00.0000000
Duration: T00H03M50S
Description: Autoimmune disease research solutions

Name: Autoimmune disease research solutions

Description: Autoimmune disease research solutions

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Upload Date: 2025-06-17T00:00:00.0000000

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Autoimmune diseases are a group of disorders that cause the immune system to mistakenly attack healthy cells, tissues, or organs. These diseases have emerged as a significant public health concern around the world, due to their increasing prevalence and the lack of available cures. On average, the prevalence of autoimmune disease is estimated to increase by 12.5% each year.
Autoimmune diseases affect people across all age groups and disproportionately affect women. Today, one in 10 individuals battle this enemy within a war waged by their own immune systems. Over 100 chronic autoimmune diseases have been found affecting every part of the body, from the joints and skin to the organs and even the nervous system. Common autoimmune diseases include rheumatoid arthritis, multiple sclerosis, psoriasis, Crohn's disease, and type 1 diabetes.
For autoimmune diseases, the detection of biomarkers such as antibodies and inflammatory markers is crucial for early diagnosis. Disease activity evaluation. Pathogenesis research and treatment. Response prediction. For instance, in rheumatoid arthritis patients, there are several lab tests for detecting the key biomarkers c-reactive protein, interleukin 6, and rheumatoid factor ELISAs are routinely used to measure these markers, helping to indicate inflammation and disease activity.
Understanding the mechanisms driving autoimmune diseases has low targets for new drugs to be identified, and advancements in autoimmune disease therapeutics to be made. This includes the development of monoclonal antibodies and small molecule drugs that target cytokines, immune cells, and protein kinases, playing a pivotal role in the treatment of autoimmune diseases. One specific targets have been identified. New drugs can be developed using recombinant proteins engineered to interact with the target.
For example, targeting the cytokine TNF alpha with adalimumab, a monoclonal antibody, can be used to treat rheumatoid arthritis. Targeting CD20 immune cells with ocrelizumab, a monoclonal antibody can be used to treat multiple sclerosis while targeting JAK3, a protein kinase with retina IB, a small molecule kinase inhibitor, has shown promise for treating alopecia areata.
Researchers are exploring new treatment methods for autoimmune diseases with adaptive immune cell therapies showing particular promise. For example, one strategy uses car-t cells against b-cell markers like CD19 to eliminate autoreactive B cells to support autoimmune disease research. Sino biological develops high quality recombinant proteins such as cytokines and active kinases. Sino biological also develops antibodies and Elisa kits to suit a wide range of applications, such as pathological mechanism research, target discovery and validation, drug development, and diagnostic kit development.
To find out more about autoimmune disease research solutions, please check out our infocus with sino biological on biotechniques.

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