Name: Sequencing for conservation
Uploaded: 2023-01-13T00:00:00.0000000
Duration: T00H02M59S
Description: Sequencing for conservation

Name: Sequencing for conservation

Description: Sequencing for conservation

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Upload Date: 2023-01-13T00:00:00.0000000

Transcript: Language: EN.
Segment:0 .
[MUSIC PLAYING]
ANNIE COULSON: In a world where environments are drastically changing, and species are going extinct at a rate between 28 and 81 times faster than the last mass extinction event, conservation efforts are crucial. Currently, there are more than 147,000 species on the International Union for Conservation of Nature's Red List of Threatened Species, with more than 41,000 species of animals, plants, and fungi, threatened with extinction. These species need intensive conservation efforts to prevent their extinction.
ANNIE COULSON: An important aspect of conservation is sequencing. Sequencing enables researchers to monitor biodiversity, assess genetic diversity within species, check for the presence of invasive species, and carry out disease surveillance. The sequencing of species allows researchers access to high quality reference genomes, which helps us understand more about species biology and physiology, phylogenetic relationships and adaptations and allows for improved markers for IDing species or even individuals.
ANNIE COULSON: For example, via environmental DNA. The remote habitats of many endangered species can make sequencing difficult, and samples are often sent to centralized locations, introducing delays and more opportunities for samples to be damaged. However, the development of portable nanopore sequencing devices, such as the minion, has allowed sequencing to be taken into the field, even in the most remote locations, enabling anyone to sequence anything, anywhere.
ANNIE COULSON: Detailed reference genomes of endangered species are integral to the success of conservation projects, providing key information regarding phylogenetic relationships, the identification of species with environmental sequencing, and a litany of other uses. The development of higher throughput platforms such as Oxford Nanopore's GridION and PromethION provide flexibility and scalability for high coverage, whole genome sequencing.
ANNIE COULSON: To support the generation and sharing of these critical reference genomes, Oxford Nanopore, NVIDIA, and EMBL-EBI, have established the ORG.one project. This project encourages the development of high quality de novo assemblies, by providing those who currently use Oxford Nanopore technologies and have access to endangered species samples, with free consumables for their work.
ANNIE COULSON: The only requirement is, for the resulting data to be uploaded to the EBI public database within six weeks of production. If you would like to find out more about the ORG.one project and how the key techniques involved are encouraging faster, localized sequencing of critically endangered species, check out our focus on the topic at, www.BioTechniques.com. [MUSIC PLAYING]

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