Name:
10.3171/2026.1.FOCVID25222_vid
Description:
10.3171/2026.1.FOCVID25222_vid
Thumbnail URL:
https://cadmoremediastorage.blob.core.windows.net/c0da0e98-5a8d-44f6-a623-3167e985a3aa/videoscrubberimages/Scrubber_90.jpg
Duration:
T00H04M30S
Embed URL:
https://stream.cadmore.media/player/c0da0e98-5a8d-44f6-a623-3167e985a3aa
Content URL:
https://cadmoreoriginalmedia.blob.core.windows.net/c0da0e98-5a8d-44f6-a623-3167e985a3aa/9. 25-222.mp4?sv=2019-02-02&sr=c&sig=E2lNwDSefgTCimvKmnOxVQqt6PhPpVAnVfbrFXy7PHM%3D&st=2026-04-05T08%3A32%3A46Z&se=2026-04-05T10%3A37%3A46Z&sp=r
Upload Date:
2026-04-05T08:37:46.7658500Z
Transcript:
Language: EN.
Segment:0 .
[UPBEAT MUSIC]
SPEAKER: Neural tube defects affect approximately 2 in 1,000 births worldwide, with myelomeningocele representing its most severe form. Prenatal repair has been shown to portend better neurologic outcomes, even despite increased maternal complications and premature birth. Minimally invasive fetoscopic approaches likely extend the benefits of prenatal repair while reducing risks. Here we show our hybrid approach to fetoscopic closure with primary closure versus an acellular dermal matrix patch.
SPEAKER: Not shown, the adult patient was positioned supine in dorsal lithotomy position. Maneuvers, when needed, are used to place the fetal patient prone in cephalic, with the head positioned in the pelvis. A midline laparotomy is created from just above the umbilicus to the pubis in order to gain access to the uterus. The uterus is then externalized and subsequently accessed using three fetoscopic ports.
SPEAKER: After identifying the area of myeloschisis, the placode is dissected from abnormal skin via the surrounding transitional arachnoid plane circumferentially with care to identify and preserve spinal cord tissue and ventral nerve roots. At the conclusion of this step, the placode can now retract back into the spinal canal. The skin is then dissected widely, again, circumferentially, in the suprafascial plane between the skin and the lumbar dorsal fascia.
SPEAKER: Skin may be opened in the midline to obtain better exposure. Myofascial flaps are raised for coverage of the placode. This is done using electrocautery, starting out laterally on both sides, then moving cranially and caudally until the myofascial flaps are mobile and easily brought to the midline, as well as long enough to cover the defect.
SPEAKER: Barbed 3-0 running V-Loc sutures are used to close the myofascial flaps over the placode and its overlying tissue graft for a watertight closure. Of note, the placode is first covered by an otologic porcine graft before bringing the myofascial flaps together over top. A suture is used at both the cranial and caudal ends, then tied together in the middle. Skin flaps are closed in the midline using a barbed 4-0 V-Loc suture with an acellular dermal matrix such as AlloDerm underlay, when primary closure is achievable with minimal tension.
SPEAKER: When this is not possible, the AlloDerm can be incorporated as a patch to minimize tension on the skin closure. In this case, the edge of the AlloDerm is sewn to the skin edges. When AlloDerm is used only as an underlay, however, the skin edges are brought together primarily over the underlay, without securing the AlloDerm to the skin.
SPEAKER: By adopting a hybrid approach that is flexible based on individual fetal anatomy, the use of AlloDerm, either under a primary closure or within the skin closure layer, promotes optimal wound healing and epithelialization over time. A suture is used at both the cranial and caudal ends, then tied together in the middle. First, we show a primary closure with AlloDerm underlay. Second, we show an incorporation of a patch.
SPEAKER: In one place, the AlloDerm patch is visible from the outside, whereas the remainder of the skin has been closed primarily. After evacuating insufflation gas, infusing warm LR back into the preoperative amniotic fluid volume and administering intrauterine nafcillin, trocars are removed and previously placed sutures are tied to close the defects. The uterus is returned to the abdomen and the laparotomy is closed in layered fashion.
SPEAKER:
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