Name:
In Focus: Small molecules
Description:
In Focus: Small molecules
Thumbnail URL:
https://cadmoremediastorage.blob.core.windows.net/c47d2a5b-f058-4c4e-8930-969ac89a4244/videoscrubberimages/Scrubber_8.jpg?sv=2019-02-02&sr=c&sig=WK7h0im0DHjuHScIS01DAYSIRuWYPD5lH42SFbSmLYg%3D&st=2024-05-10T21%3A36%3A11Z&se=2024-05-11T01%3A41%3A11Z&sp=r
Duration:
T00H01M58S
Embed URL:
https://stream.cadmore.media/player/c47d2a5b-f058-4c4e-8930-969ac89a4244
Content URL:
https://cadmoreoriginalmedia.blob.core.windows.net/c47d2a5b-f058-4c4e-8930-969ac89a4244/RMN In Focus %e2%80%93 Bio-Techne %e2%80%93 small molecules V1.mp4?sv=2019-02-02&sr=c&sig=ZPyd1BMzAFZmBuRxk3x4uX77VyBc%2BWMRBqcgs6%2Fn5QM%3D&st=2024-05-10T21%3A36%3A11Z&se=2024-05-10T23%3A41%3A11Z&sp=r
Upload Date:
2023-08-08T00:00:00.0000000
Transcript:
Language: EN.
Segment:0 .
SPEAKER: Hello and welcome to RegMedNet. This month, we are focusing on enhanced quality small molecules as ancillary materials. Small molecules are used throughout the development of induced pluripotent stem cell derived cell therapies in much the same way as protein growth factors. They can be used to replace the Yamanaka factors that play a vital role in reprogramming somatic cells, can maintain healthy cells during expansion phases, and are highly effective in driving differentiation to the final cell product.
SPEAKER: Small molecules have a number of advantages over genetic manipulation, particularly around the ease of handling, temporal control of the addition, and the ability to scale up. Choosing the right reagent supplier can be difficult because it's not always clear which guidelines cell therapy manufacturers should be following around using small molecules as ancillary reagents or raw materials in their cell therapy development process.
SPEAKER: In addition, the key quality attributes of small molecules versus proteins or other media components are quite different. Knowing which quality aspects to focus on can be critical to anticipating and preempting the future requirements of regulators. In this In Focus feature, in association with Bio-Techne, we'll be exploring the application of small molecules for stem cell derived cell therapies and investigating how to choose the right quality reagents as an essential part of the development process.
SPEAKER: Experts from Bio-Techne will share their insights on where small molecules can potentially enhance your cell therapy processes. What quality control specifications are most applicable for chemical reagents? And how manufacturers can enhance the quality of their products? Join the conversation today at regmednet.com or follow the discussion on Twitter, Facebook, and LinkedIn.
SPEAKER: We'll see you there.